Health · Disorders
which genetic variants increase susceptibility to treatment-resistant bipolar disorder?
Genetic factors that influence why some people have poor response to standard therapies often overlap with the biology underlying bipolar disorder itself, while other variants specifically affect medication response pathways.
do hormonal contraceptives exacerbate pre-existing mood disorders?
Hormonal contraceptives can affect mood, and for some people they may worsen pre-existing mood disorders, but the evidence is mixed and individual. Large observational studies have reported associations between hormonal
does chronic vestibular dysfunction increase dementia risk later in life?
Chronic vestibular dysfunction has been linked to higher rates of cognitive decline in several clinical and imaging studies, but the relationship is complex and not strictly proven as causal. Research
what role do microplastics play in endocrine disorder risk?
Microplastics influence endocrine disorder risk primarily by acting as carriers of endocrine-disrupting chemicals and by generating biological responses that can alter hormone systems. Particles smaller than five millimeters are pervasive
how should benzodiazepines be tapered to minimize withdrawal disorders?
Tapering benzodiazepines to minimize withdrawal disorders requires a structured, patient-centered approach grounded in evidence and clinical experience. C. Heather Ashton of the University of Newcastle upon Tyne described a widely
how does urban air pollution contribute to development of anxiety disorders?
Urban air pollution affects mental health through multiple biologic and social pathways, contributing to higher rates of anxiety disorders in exposed populations. Epidemiological research links long-term exposure to fine particulate
are recurrent urinary tract infections a hidden driver of accelerated cognitive decline in postmenopausal women?
The evidence indicates that infections — including urinary tract infections — are associated with increased risk of later-life cognitive decline, but calling recurrent urinary tract infections a proven hidden driver
do social media algorithms worsen symptoms in adolescents with eating disorders?
Social media algorithms can contribute to worsening symptoms in adolescents with eating disorders by selectively exposing vulnerable users to appearance-focused and pro-disorder content. Research indicates a consistent association between image-based
which biomarkers predict autoimmune encephalitis relapse after immunotherapy?
Autoimmune encephalitis relapse risk after immunotherapy is associated with a combination of immunological, neuronal injury, imaging, and clinical markers. Evidence from leading centers shows that some tests carry stronger predictive
are sleep disturbances early indicators of neurodegenerative movement disorders?
Sleep disturbances can precede clear motor symptoms in several neurodegenerative movement disorders, most convincingly in conditions tied to abnormal alpha-synuclein accumulation. Clinical researchers and sleep neurologists emphasize that certain sleep