Health
how do advertising practices influence prescription opioid misuse rates?
Aggressive commercial promotion of opioid products altered clinician perceptions of benefits and risks and contributed to higher prescribing volumes that increased opportunities for misuse. Roger A. Van Zee Dartmouth-Hitchcock Medical
does long-term proton pump inhibitor use increase risk of enteric infections?
Long-term use of proton pump inhibitors is associated with an increased risk of enteric infections, with the strongest and most consistent evidence linking these drugs to Clostridioides difficile infection. L.
which genetic variants increase susceptibility to treatment-resistant bipolar disorder?
Genetic factors that influence why some people have poor response to standard therapies often overlap with the biology underlying bipolar disorder itself, while other variants specifically affect medication response pathways.
how effective are community gardens at improving adult nutritional health?
Community gardens can contribute to improved adult nutritional health, but their effectiveness varies with context, program design, and population. Public health organizations summarize consistent associations between gardening and dietary benefits
which micronutrient deficiencies most impair wound healing in adults?
Wound repair in adults is most sensitive to deficiencies of several micronutrients that support collagen production, immune defense, oxygen delivery, and cellular proliferation. Evidence from the Office of Dietary Supplements
how do exercise breaks during workdays impact long-term musculoskeletal health?
Regular, brief exercise breaks during the workday are associated with measurable benefits for long-term musculoskeletal health. Research led by Lars L. Andersen at the National Research Centre for the Working
which medications interact with stress to increase cardiovascular risk?
Medications can magnify the cardiovascular effects of psychological or physical stress by amplifying sympathetic activation, raising blood pressure, promoting arrhythmia, or altering coagulation. Acute stressors are established triggers for myocardial
how does session frequency affect outcomes in short-term psychotherapy?
Short-term psychotherapy outcomes depend not only on the therapeutic model but on session frequency, which shapes how quickly and sustainably patients improve. Research synthesizing many trials suggests that higher-frequency contact
do needle-free vaccine delivery methods improve uptake among needle-phobic adults?
Needle-free vaccine delivery methods can increase vaccination among adults who avoid injections, but effects depend on technology, context, and trust. Evidence from acceptability and early clinical work shows that alternatives
how does air pollution exposure influence risk of substance use disorders?
Air pollution exposures are increasingly recognized as a contributor to vulnerabilities in mental health and substance use. Evidence from environmental health research links airborne particulate matter and combustion-related pollutants to